Dr. David Ludwig in the News: 2019 – 2021
Swipe left to see more articles.
Challenging Dietary Dogma on Weight Gain
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
"We’ve Had it Backwards" - New Model Explains Weight Gain and Obesity
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
Stimulated Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
Effects of a low-carbohydrate diet on insulin-resistant dyslipoproteinemia—a randomized controlled feeding trial
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
CAN A LOW-CARB DIET HELP YOUR HEART HEALTH?
OP-ED: DO WE REALLY KNOW WHAT MAKES US FAT?
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
Do Lower-Carbohydrate Diets Increase Total Energy Expenditure?
DECEMBER 3, 2020: “Conclusion: Lower-carbohydrate diets transiently reduce TEE, with a larger increase after ∼2.5 wk. These findings highlight the importance of longer trials to understand chronic macronutrient effects and suggest a mechanism whereby lower-carbohydrate diets may facilitate weight loss.”
Effects of Sugar‐Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors...
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
Effects of Dietary Carbohydrate Content on Circulating Metabolic Fuel Availability in the Postprandial State
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
Milk and Health
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
WHY DIET RESEARCH IS SO SPECTACULARLY THIN
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
DISCREPANCIES IN THE REGISTRIES OF DIET VS DRUG TRIALS
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
Improving the Quality of Dietary Research
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Dr. David Ludwig in the News: 2016 – 2018
Swipe left to see more articles.
Challenging Dietary Dogma on Weight Gain
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
"We’ve Had it Backwards" - New Model Explains Weight Gain and Obesity
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
Stimulated Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
Effects of a low-carbohydrate diet on insulin-resistant dyslipoproteinemia—a randomized controlled feeding trial
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
CAN A LOW-CARB DIET HELP YOUR HEART HEALTH?
OP-ED: DO WE REALLY KNOW WHAT MAKES US FAT?
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
Do Lower-Carbohydrate Diets Increase Total Energy Expenditure?
DECEMBER 3, 2020: “Conclusion: Lower-carbohydrate diets transiently reduce TEE, with a larger increase after ∼2.5 wk. These findings highlight the importance of longer trials to understand chronic macronutrient effects and suggest a mechanism whereby lower-carbohydrate diets may facilitate weight loss.”
Effects of Sugar‐Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors...
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
Effects of Dietary Carbohydrate Content on Circulating Metabolic Fuel Availability in the Postprandial State
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
Milk and Health
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
WHY DIET RESEARCH IS SO SPECTACULARLY THIN
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
DISCREPANCIES IN THE REGISTRIES OF DIET VS DRUG TRIALS
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
Improving the Quality of Dietary Research
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Dr. David Ludwig in the News: 2014-2015
Swipe left to see more articles.
Challenging Dietary Dogma on Weight Gain
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
"We’ve Had it Backwards" - New Model Explains Weight Gain and Obesity
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
Stimulated Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
Effects of a low-carbohydrate diet on insulin-resistant dyslipoproteinemia—a randomized controlled feeding trial
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
CAN A LOW-CARB DIET HELP YOUR HEART HEALTH?
OP-ED: DO WE REALLY KNOW WHAT MAKES US FAT?
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
Do Lower-Carbohydrate Diets Increase Total Energy Expenditure?
DECEMBER 3, 2020: “Conclusion: Lower-carbohydrate diets transiently reduce TEE, with a larger increase after ∼2.5 wk. These findings highlight the importance of longer trials to understand chronic macronutrient effects and suggest a mechanism whereby lower-carbohydrate diets may facilitate weight loss.”
Effects of Sugar‐Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors...
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
Effects of Dietary Carbohydrate Content on Circulating Metabolic Fuel Availability in the Postprandial State
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
Milk and Health
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
WHY DIET RESEARCH IS SO SPECTACULARLY THIN
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
DISCREPANCIES IN THE REGISTRIES OF DIET VS DRUG TRIALS
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
Improving the Quality of Dietary Research
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Dr. David Ludwig in the News: 2010-2013
Swipe left to see more articles.
Challenging Dietary Dogma on Weight Gain
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
"We’ve Had it Backwards" - New Model Explains Weight Gain and Obesity
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
Stimulated Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
Effects of a low-carbohydrate diet on insulin-resistant dyslipoproteinemia—a randomized controlled feeding trial
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
CAN A LOW-CARB DIET HELP YOUR HEART HEALTH?
OP-ED: DO WE REALLY KNOW WHAT MAKES US FAT?
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
Do Lower-Carbohydrate Diets Increase Total Energy Expenditure?
DECEMBER 3, 2020: “Conclusion: Lower-carbohydrate diets transiently reduce TEE, with a larger increase after ∼2.5 wk. These findings highlight the importance of longer trials to understand chronic macronutrient effects and suggest a mechanism whereby lower-carbohydrate diets may facilitate weight loss.”
Effects of Sugar‐Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors...
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
Effects of Dietary Carbohydrate Content on Circulating Metabolic Fuel Availability in the Postprandial State
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
Milk and Health
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
WHY DIET RESEARCH IS SO SPECTACULARLY THIN
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
DISCREPANCIES IN THE REGISTRIES OF DIET VS DRUG TRIALS
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
Improving the Quality of Dietary Research
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Dr. David Ludwig in the News: Earlier than 2010
Swipe left to see more articles.
Challenging Dietary Dogma on Weight Gain
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
"We’ve Had it Backwards" - New Model Explains Weight Gain and Obesity
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
Stimulated Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
Effects of a low-carbohydrate diet on insulin-resistant dyslipoproteinemia—a randomized controlled feeding trial
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
CAN A LOW-CARB DIET HELP YOUR HEART HEALTH?
OP-ED: DO WE REALLY KNOW WHAT MAKES US FAT?
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
Do Lower-Carbohydrate Diets Increase Total Energy Expenditure?
DECEMBER 3, 2020: “Conclusion: Lower-carbohydrate diets transiently reduce TEE, with a larger increase after ∼2.5 wk. These findings highlight the importance of longer trials to understand chronic macronutrient effects and suggest a mechanism whereby lower-carbohydrate diets may facilitate weight loss.”
Effects of Sugar‐Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors...
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
Effects of Dietary Carbohydrate Content on Circulating Metabolic Fuel Availability in the Postprandial State
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
Milk and Health
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
WHY DIET RESEARCH IS SO SPECTACULARLY THIN
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
DISCREPANCIES IN THE REGISTRIES OF DIET VS DRUG TRIALS
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
Improving the Quality of Dietary Research
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Always Hungry?
Available now on
