

Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
(SEPTEMBER 28, 2021): Overweight people who ate fewer carbohydrates and increased their fat intake had significant improvements in their cardiovascular disease risk factors.
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
(SEPTEMBER 28, 2021): Overweight people who ate fewer carbohydrates and increased their fat intake had significant improvements in their cardiovascular disease risk factors.
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
(SEPTEMBER 28, 2021): Overweight people who ate fewer carbohydrates and increased their fat intake had significant improvements in their cardiovascular disease risk factors.
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
(SEPTEMBER 28, 2021): Overweight people who ate fewer carbohydrates and increased their fat intake had significant improvements in their cardiovascular disease risk factors.
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.
Introduction to Podcast (Starts at 6:10): Our guests are challenging the dietary dogma on weight gain, that we put on weight because we eat too much and move too little. Read More >>
November 9, 2021: Intro to Video: “A paper just released in the American Journal of Clinical Nutrition challenges really challenges conventional thinking about nutrition, weight gain, and what has caused the very rapid and profound increase in obesity rates over the last 50 years. This is a landmark paper by any standard and saying that will raise eyebrows is an understatement. The papers authored by a number of distinguished nutrition scientists. The lead author is Dr. David Ludwig from Harvard University.”
SEPTEMBER 29, 2021: CONCLUSIONS: Baseline insulin dynamics predict substantial individual differences in body composition following weight loss. These findings may inform understanding of the pathophysiological basis for weight regain and the design of more effective obesity treatment.
SEPTEMBER 28, 2021: “Conclusion: A low-carbohydrate diet, high in saturated fat, improved insulin-resistant dyslipoproteinemia and lipoprotein(a), without adverse effect on LDL cholesterol. Carbohydrate restriction might lower CVD risk independently of body weight, a possibility that warrants study in major multicentered trials powered on hard outcomes.”
SEPTEMBER 13, 2021: “According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may arise from a fundamental limitation of the EBM itself. ”
(SEPTEMBER 28, 2021): Overweight people who ate fewer carbohydrates and increased their fat intake had significant improvements in their cardiovascular disease risk factors.
(SEPTEMBER 26, 2021): “We’re familiar with the pattern by now: Every few years, a new study emerges with new obesity statistics. The numbers seem shockingly high, almost impossibly high, until the next study comes along with numbers that are higher still. In the 1970s, approximately 15% of American adults met the obesity criteria. By the end of the 1980s, that 15% had grown to more than 20%. By the year 2000, we had reached 30%. Today, 42% of American adults are classified as obese, and an additional 30% are considered overweight. Whatever is happening, it is happening to a remarkable number of us.”
JULY 22, 2020: A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar‐sweetened beverages (SSBs) during transition to unsweetened beverages (USBs).
MAY 26, 2020: “According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy.”
FEBRUARY 13, 2020: This review summarizes the evidence for the benefits and possible risks associated with consumption of cow’s milk. The authors describe the relationship of milk consumption to the risks of fracture, obesity, cardiovascular disease, allergies, and various cancers.
DECEMBER 11, 2019: “For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes.”
NOVEMBER 2019 – Most diet trials in the best journals fail even the most basic of quality control measures. That’s the finding of a study by us to be published today in JAMA Network Open.
NOVEMBER 13 2019 – ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials.
AUGUST 12, 2019: “Compared with pharmaceutical research, studies evaluating diet or dietary interventions for chronic diseases like obesity (to be distinguished from micronutrient deficiency syndromes like scurvy or rickets) have far greater challenges in terms of consistency, quality control, confounding, and interpretation.”
CONCLUSIONS: Exceptional glycemic control of T1DM with low rates of adverse events was reported by a community of children and adults who consume a VLCD. The generalizability of these findings requires further studies, including high-quality randomized controlled trials.